Rosuvastatin is a medicine that is prescribed to lower LDL cholesterol and triglyceride levels. High levels of these lipids in the blood can lead to fat deposits along the walls of the blood vessels. This can narrow and clog these vessels, increasing the risk of a heart attack or stroke.

This medicine can be found in pharmacies in the form of 5, 10, 20 and 40 mg tablets, under the brand name Crestor or in its in generic form under the name “rosuvastatin calcium.” A prescription is necessary for dispensing it.

Rosuvastatin can also be found in combination with ezetimibe, which is a substance that acts by reducing the absorption of fats in the gut. This can further help to reduce high cholesterol and triglyceride levels..

What is it used for?

Rosuvastatin is indicated to reduce the levels of total cholesterol, LDL cholesterol and triglycerides in the blood. It can also promote the increase of HDL cholesterol, as it works by inhibiting an enzyme in the liver that is responsible for the production of LDL cholesterol.

This medication is generally indicated when diet and physical activity are not enough to reduce or control cholesterol levels.

Rosuvastatin may be indicated to slow or reduce the accumulation of fat in blood vessels, which can block blood flow. Therefore, it can help to reduce the risk of cardiovascular diseases like a heart attack or stroke.

Rosuvastatin should be taken as prescribed by a cardiologist, and with regular medical monitoring to evaluate cholesterol levels and the appearance of side effects.

Can rosuvastatin lead to weight gain?

Rosuvastatin can lead to weight loss as it can decrease appetite and reduce calorie intake throughout the day. However, it is not medically indicated for weight loss objectives, as this medication is only approved for the treatment of high cholesterol and/or triglycerides.

Rosuvastatin should be taken as part of a a balanced diet and active lifestyle to manage cholesterol and triglyceride levels, which can contribute to weight loss.

How to take

Rosuvastatin should be taken orally, with a glass of water, in a single daily dose, with or without food, at any time of the day. However, it is recommended to set a specific time to take the pill, and to take it at the same time each day.

The recommended doses of rosuvastatin for adults are 10 to 40 mg, as prescribed by your doctor. Dosing depends on the objective of the treatment, as well as each person's response to the treatment.

If necessary, the doses of rosuvastatin can be changed by the doctor, at intervals of 2 to 4 weeks. Dosing, for example, can be altered depending on blood test results. The maximum daily dose is 40 mg of rosuvastatin.

For children and adolescents aged 6 to 17, doses should be prescribed by a pediatrician, as dosing can vary depending on age and treatment goals.

Treatment with rosuvastatin is usually long-term should not be interrupted.

When it takes effect

The effects of rosuvastatin can be noted after about 4 weeks of taking the medicine. Lipid levels will start to normalize when treatment is consistent and at a therapeutic dose.

Possible side effects

The most common side effects of rosuvastatin include headache, muscle pain, general weakness, constipation, dizziness, nausea or abdominal pain.

Although it is rare, rosuvastatin can lead to serious side effects that require immediate medical attention, such as muscle pain in the hips, shoulders, neck or back, difficulty lifting the arms, climbing stairs or standing, mental confusion, memory problems, loss of appetite, pancreatic inflammation, or liver problems, which may present with symptoms like dark urine, pale stools, or yellow skin and eyes.

It is advisable to seek medical attention immediately or proceed to the nearest emergency room if symptoms of a serious allergic reaction develop after taking rosuvastatin. Signs of a serious allergic reaction include difficulty breathing, feeling of a closed throat, swelling of the mouth, tongue or face, or hives.

Contraindications for use

Rosuvastatin should not be taken by children under 6 years of age, pregnant or breastfeeding women. It should not be taken by people with liver or kidney failure, hypothyroidism, or who frequently consume alcohol.

In addition, this medicine should not be used by people who are allergic to rosuvastatin or any other component in the tablets.

When taking rosuvastatin, you should avoid drinking alcohol, as this can increase your risk for liver problems. Some antacids containing aluminum or magnesium can also interfere with the effect of rosuvastatin, and therefore you should aim to take antacids approximately 2 hours after taking the dose of rosuvastatin.

Your doctor should be informed of all medications you may be taking, as well as any dietary supplements, herbal remedies, and home remedies, as they can interfere with the action of rosuvastatin.